BackgroundThe relationship between sleep disorders and psychiatric disorders has been extensively studied in epidemiological research. However, whether specific sleep-related traits are associated with psychiatric…
BackgroundThis study examined prefrontal activation and functional connectivity during a fixed phrase verbal fluency task (VFT) in children with Autism Spectrum Disorder (ASD) compared to basic information- and…
BackgroundContinuous Traumatic Stress Response (CTSR) refers to psychological, emotional, and behavioral reactions that emerge under conditions of ongoing, realistic, and future-oriented threat. Recently, CTSR received…
BackgroundAttempted suicide is one of the most serious clinical consequences for patients with depression, and early identification of high-risk individuals is crucial for preventing suicide deaths. Traditional clinical…
IntroductionEarly maladaptive schemas (EMS) have been increasingly recognized as key cognitive vulnerability factors in depression. This study aimed to evaluate the effects of antidepressant treatment on early…
BackgroundFrequent extreme heat events have become a prominent feature of climate change. However, their potential impact on adolescent mental health and the underlying pathways remain unclear. This study aimed to…
BackgroundIndividuals with Schizophrenia are often reported to suffer from sexual dysfunction, but despite its clinical and individual relevance, the underlying neural mechanisms have not been investigated. To date it is…
BackgroundExercise intervention has been associated with cognitive development in children. However, current study methods have not clarified the potential nonlinear association between exercise dosage and cognitive…
BackgroundDepressive disorder is a leading cause of disability worldwide, and selective serotonin reuptake inhibitors (SSRIs) remain first-line pharmacotherapy. However, the efficacy and safety of adding Chinese patent…
(MedPage Today) -- The FDA granted accelerated approval to the first cereblon E3 ligase modulation (CELMoD) therapy for relapsed or refractory multiple myeloma, the agency announced on Thursday. An oral drug, iberdomide…
(MedPage Today) -- Luigi Mangione is expected to plead guilty as early as Friday in the federal case accusing him of stalking and killing UnitedHealthcare CEO Brian Thompson, according to a person familiar with the…
Companies that manufacture MDMA and psilocybin for patients in other countries are looking to use their experience to access the potential U.S. market.
(MedPage Today) -- Bariatric surgery patients who took GLP-1 medications prior to surgery lost the same amount of weight after 1 year as individuals unexposed to the blockbuster class of drugs, a retrospective review…
Scenario 1: Your patient is an executive at large company and experiences anxiety before the weekly board meeting. She wishes there were a simple strategy to help her cope.Scenario 2: Your patient is a medical student…
(MedPage Today) -- Defying expectations, regular cannabis users had fewer ectopic heartbeats on the days they reached for the joint or vape, a randomized crossover trial showed. On days using cannabis, there was a…
(MedPage Today) -- The JAK inhibitor upadacitinib (Rinvoq) dramatically improved hair regrowth for patients with severe alopecia areata in two parallel phase III trials, with results that appeared better than previously…
(MedPage Today) -- While the use of focal therapy for nonmetastatic prostate cancer is limited, half of procedures occurred in settings that are not supported by current guidelines, according to a retrospective study…
Families of children with autism spectrum disorder (ASD) can face immense daily burdens due to a combination of severe food selectivity, motor impairments, sensory dysregulation and social challenges. In clinical…
Women who used estrogen-only menopausal hormonal therapy later in life had lower risks for neuropathologic and clinical outcomes related to Alzheimer’s disease, according to data published in Neurology.“As part of an…
Combining ketamine and psychotherapy is a safe and feasible approach with promising benefits for people experiencing chronic neuropathic pain, according to a new study by researchers at St. Michael's ...
Entactogen research targets social anxiety and isolation across diagnoses, pairing “plasticity windows” with psychotherapy amid shifting FDA scrutiny and evolving trial designs.
NICU stays can affect more than an infant’s health, causing a lasting impact on the family and the parents’ mental well-being.Interventions can help ease these stresses beyond the hospital stay.As a pediatric…
"...time slowed to the tide’s rhythm and the surf’s roar, each day closed by a Great Horned Owl’s silent fly-by at dusk..."
A woman found out she had an attention-seeking personality disorder that led her to get married for “validation” – after she watched a documentary about a murderer with the same condition. Dayzee Bell ...
BackgroundTreatment resistant depression (TRD) is a burdensome condition with a severe impact on patients’ everyday lives. Therapeutics have improved in the last decade, however, outcomes remain poor. Real-world…
IntroductionPhysical appearance, including body weight and clothing, can affect perceptions of physicians’ empathy and competence, thereby shaping the quality of the patient–physician relationship. Understanding these…
Background and objectiveWar-related mass trauma and large-scale terrorist attacks disproportionately affect clinically vulnerable adolescents, exacerbating self-harm and suicidality while burdening under-resourced public…
ObjectiveTo investigate cerebral and cervical hemodynamic differences assessed by transcranial color-coded duplex sonography (TCCD) combined with cervical artery ultrasound in adolescents with first-episode depressive…
Adolescent depression and anxiety are common, heterogeneous, and often recognized late. Young people may present with sleep disturbance, irritability, somatic complaints, school refusal, social withdrawal, attentional…
With interest in the adoption of artificial intelligence (AI)-enabled digital mental health technologies (AI-DMHTs) among the general population ceaselessly escalating, mental health clinicians are obliged to confront…