Researchers have developed a predictive algorithm using brain connectivity and behavioral tests to forecast antidepressant outcomes. A recent study suggests this tool can identify depressed patients who are highly likely…
High levels of a specific blood protein during midlife suggest an increased risk for vascular dementia. Researchers found evidence that this protein might alter immune activity and contribute to the gradual loss of…
Dietary arginine reduces tumor formation and viral load in mice by boosting key immune proteins.
A pilot clinical trial suggests that psilocybin combined with psychotherapy is safe and well-tolerated by veterans with severe, treatment-resistant PTSD. The study found that most participants no longer met the…
Discover nine traits that research links to attraction, showing why confidence, kindness, and authenticity often matter more than appearance alone.
Astronauts are notoriously slow and deliberate when moving in space. But a new study from the China Space Station reveals it’s not just about safety—microgravity actually tricks the human brain into underestimating its…
A canopy call, a partial photo and DNA revealed a new primate species — one that may already be at risk of extinction.
A recent study provides evidence that people experiencing long COVID show a measurable reduction in the brain’s dopamine-releasing neurons. These physical changes tend to be associated with persistent symptoms like…
There are roughly 220 million adults in China age 65 or older, more than twice as many as 20 years ago, with 1 in 5 currently reporting depressive symptoms.
Adults who experienced psychological maltreatment as children often report lower satisfaction in romantic partnerships. By tracking young adults over time, researchers found that this early abuse diminishes relationship…
New brain scans show that drugs like LSD, psilocybin, and MDMA reliably reduce the upward flow of information into a core brain network. This surprising shift offers a biological explanation for their psychological risks…
Odysseus did not face the parasite Cyclospora in his 10-year journey home. But the word "parasite" originated as a popular character trope in Greek literature.
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceCellular function depends on stability under fluctuating conditions that occur across diverse timescales. Biomolecular…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceHumans adapt by learning from others, but risk acquiring maladaptive behaviors when learning from individuals facing…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceOocytes remain quiescent for decades to preserve reproductive capacity, relying on the sustained expression of key proteins…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceAutism spectrum disorder (ASD) is strongly linked to synaptic dysfunction, yet the contribution of presynaptic processes to…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceLiving organisms possess enzymes that hydrolyze inosine triphosphate (ITP). In humans, inosine triphosphatase (ITPA)…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceUbiquitination is a key posttranslational modification in eukaryotes that plays a critical role in diverse cellular…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceDespite the global success of folic acid (FA) supplementation in preventing neural tube defects (NTDs), the medical…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceCells compartmentalize biochemistry using biomolecular condensates formed by phase separation. Although cells contain…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceRetron Ec78 participates in prokaryotic immune responses using a two-component effector complex PtuAB comprising an ABC…
Hungary is often portrayed as an exceptional case of democratic backsliding driven by unique political and cultural conditions. We tested this view by analyzing five waves of European Social Survey data from Hungary…
IntroductionAllostatic load (AL) reflects the cumulative physiological burden on the body, quantified using biomarkers across multiple systems. The current study identified latent AL profiles in young adults and examined…
BackgroundThe rapid development of generative artificial intelligence (AI) is reshaping the higher education ecosystem, and the application of AI in teaching is becoming increasingly widespread. However, many teachers…
IntroductionWith the proliferation of digital technologies, research on virtual reality-assisted music therapy (VR-assisted MT) has expanded across clinical, rehabilitation, and wellness contexts. This scoping review…
BackgroundMedical students experience substantial academic and demands that can adversely affect their academic wellbeing. Although perceived social support is a recognized protective factor, its relationship with…
ObjectiveSerum free thyroxine (FT4) has been demonstrated to be associated with human aggression. Based on the theoretical and empirical research on hostile attribution bias and psychological resilience, this study…
This study examines a search-defined body of STEM career-choice literature retrieved through queries combining STEM-related, career-related, gender-related, and psychosocial-construct terms, including identity…
IntroductionAdolescence is a critical developmental period during which young people experience significant academic, emotional, and social challenges. While whole-child developmental frameworks advocate integrating…
BackgroundData fairness has become an increasingly important issue in the digital economy. Although social media platforms extensively collect and utilize personal data, limited research has examined how users perceive…