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Levodopa combined with a peripheral DOPA decarboxylase inhibitor (DDCI) is the first-line treatment for Parkinson’s disease (PD), yet interindividual response variability remains poorly understood. Whether DDCIs…
Rare genetic variants in the glycine receptor (GlyR) α2 subunit gene (GLRA2) are associated with autism spectrum disorder, developmental delay, and intellectual disability, often accompanied by microcephaly, language…
Olfactory groove meningiomas (OGMs) are slow-growing tumors that compress the orbitofrontal cortex, potentially causing executive dysfunction, affective disturbances and behavioral alterations. However, prospective…
Post-stroke depression (PSD) is a common complication among stroke survivors and is closely associated with executive function deficits, yet effective treatments targeting both domains remain limited. Transcutaneous…
As the population continues to age, a rise in the number of individuals experiencing mild cognitive impairment or dementia symptoms is anticipated. Brain atrophy is strongly associated with cognitive decline that could…
Glioblastoma multiforme (GBM) remains a highly lethal brain malignancy, and although maximal surgical resection can improve outcomes, many tumors are not amenable to aggressive surgery due to proximity to critical…
Understanding how the brain evaluates aversion and appetition to guide behavior is an important question. Here, we investigated the role of dopamine signaling in the tail of the striatum (TS) in regulating competing…
Behavioral state fluctuations profoundly impact episodic memory processing. To explore the underlying mechanisms, we recorded CA1 place cells in head-fixed male mice and focused on awake immobility to capture spontaneous…
Neurodegenerative disorders, such as Alzheimerâs, dementia, and Parkinsonâs disease, pose a significant worldwide health concern owing to their progressive and irreversible nature. Early and precise prediction of…
Stereotypical motor movements (SMM) are a core diagnostic feature of autism and remain difficult to quantify across individuals and developmental stages in an efficient and valid way. The current paper presents a novel…
Influenced by Regulatory Focus Theory, message framing is crucial in persuasive communication, particularly in marketing. This effect is further enhanced when integrated with artificial intelligence-generated content…
In the version of the article initially published, Corey C. Harwell was inadvertently omitted from the author list. Corey C. Harwellâs laboratory, in collaboration with Christopher M. Reid, generated the unpublished…
The mediators and moderators of the effect of mindfulness- and compassion-based interventions (MCBIs) on parental burnout are not yet well understood. This study examined the impact of an MCBI on parental burnout in…
Humans prioritize learning about kinds (e.g., dogs, in general), over individuals (e.g., a specific dog), as kind-based facts provide rich information about categories that support learning. However, to build a…
Resilience is a dynamic process of adapting to stress. Identifying modifiable resilience factors (RFs) remains challenging due to the difficulty of studying individuals before, during, and after a stressor in real time…
The aim of this study is to create a biblio-systematic review that maps trends in research concerning resilience of L2 teachers. The review summarizes literature published 24 articles between 2017 and 2024 on resilience…
Efficient search and rescue (SAR) operations depend on tools and strategies that can understand and predict the behavior of lost individuals. Traditional methods, like the distance-ring model, assume uniform speed and…
Parental divorce is known to negatively affect adolescentsâ academic motivation. However, limited research has examined whether social support from teachers and peers can buffer these effects, leaving a gap in…
Communication confidence may support sustained second language (L2) learning, while burnout may be associated with learners’ intention to continue. This issue is especially relevant in intensive L2 Arabic programs in…
Family conflict is a prevalent source of stress in childrenâs lives and has important implications for child mental health, particularly when conflict is severe and destructive. Prior research has documented…
Background: Problematic social media use, particularly TikTok, has raised growing concern due to its potential negative effects on young people’s mental health. Addressing this phenomenon requires valid and reliable…
An important but under-explored use case for socially assistive robotics is in community formation. In this work, we conduct a novel investigation into the ability of a social robot to encourage human-human relationships…
Sensory difficulties in attention deficit hyperactivity disorder (ADHD) exacerbate behavioural and emotional challenges. Despite their clinical prevalence, objective psychophysical assessments of sensory performance in…
Background Ostracism on social media is a common and emotionally salient stressor. However, its moment-to-moment psychological and behavioral consequences, remain poorly understood in individuals with Non-Suicidal…
Background Early life adversity (ELA) is associated with increased internalizing and externalizing behavior in high-income cohorts. However, it is unclear whether these associations generalize to low- and middle-income…
Background This study examined whether self-esteem mediates the association between perceived social support and youth mental health difficulties in a heterogeneous sample of school-recruited youths and clinically…
The “Hopkins Competency Assessment Test” (HCAT) assesses a patient’s ability to provide written informed consent or advance directives. It includes an essay for three reading difficulty levels (12th, 8th, and 6th school…
To screen significantly differential metabolites between schizophrenia (SZ) patients and healthy controls using univariate analysis combined with orthogonal partial least squares discriminant analysis (OPLS-DA), and to…
Background Caregivers of individuals with schizophrenia face emotional and psychological challenges that affect their subjective well-being (SWB). Despite their vital role, caregiver-focused interventions are limited…
Sexual dysfunction and distress are common among depressed patients and significantly affect their quality of life. This study aims to determine the prevalence of sexual dysfunction and distress and identify potential…
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